Lymphoma Lymphoma Manuel Noriega Category="Blood disorders"Category="Oncology"Category="Types of cancer"Lymphoma is a general term for malignancies of lymphocytes or, more rarely, of histiocytes. Collectively, these cell types form the Reticuloendothelial system and circulate in the vessels of the Lymphatic system. Traditionally, Lymphoma is classified as Hodgkin's lymphoma, discovered by Thomas Hodgkin in 1832, and Non-Hodgkin's lymphoma (all other types of lymphoma). Modern classifications of lymphoma have moved away from this artificial division.

Classification

Working Formulation

The Working Formulation, published in 1982, is primarily descriptive but remains the most widely used classification of non-Hodgkin lymphoma today.

Low Grade

Intermediate Grade

High Grade

Miscellaneous

REAL/WHO Classification

The WHO Classification is the latest classification of lymphoma, published by the World Health Organization in 2001. It was based upon the "Revised European-American Lymphoma classification" (REAL) and is sometimes referenced by that name.

This classification attempts to classify lymphomas by cell type, i.e. the normal cell type that most closely resembles the tumour. They are classified in three large groups: the B cell tumours, the T cell and Natural killer cell tumours, Hodgkin lymphoma, and other minor groups:

Mature B cell Neoplasms

Mature T cell and Natural Killer (NK) Cell Neoplasms

Hodgkin Lymphoma

Immunodeficiency-Associated Lymphoproliferative Disorders

Histiocytic and Dendritic cell Neoplasms

Other classification systems

Prevalence

According to the U.S. National Institutes of Health, lymphomas account for about five percent of all cases of cancer in the United States, and Hodgkin's disease in particular accounts for less than one percent of all cases of cancer in the United States.

See also

External links

Health science - Medicine - Hematology
Hematological malignancy and White blood cells
Leukemia (ALL, AML, CLL, CML) - Lymphoma (Hodgkin's disease, NHL) - Multiple myeloma - MDS - Myelofibrosis - Myeloproliferative disease (Essential thrombocytosis, Polycythemia) - Neutropenia
Red blood cells
Anemia - Hemochromatosis - Sickle-cell disease - Thalassemia - Hemolysis - G6PD - Hereditary spherocytosis - other hemoglobinopathies
Coagulation and Platelets
Thrombosis - Deep vein thrombosis - Pulmonary embolism - Hemophilia - ITP - TTP