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1527
EventsBirths - March 21 - Hermann Finck, German composer and music theorist (died 1558)
- April 14 - Abraham Ortelius, Flemish cartographer and geographer (died 1598)
- July 13 - John Dee, English mathematician, astronomer, and geographer (died 1608)
- July 31 - Maximilian II, Holy Roman Emperor (died 1576)
- October 21 - Louis I, Cardinal of Guise, French cardinal (d. 1578)
- Giuseppe Arcimboldo, Italian artist (died 1593)
- Charles of Guise, French cardinal (died 1574)
- Lawrence Humphrey, English clergyman and educator (died 1590)
- Luis Ponce de León, Spanish lyric poet (died 1591)
- Sakuma Nobumori, Japanese retainer and samurai (died 1581)
- Annibale Padovano, Italian composer and organist (died 1575)
Deaths - January 21 - Juan de Grijalva, Spanish conquistador (born 1489)
- June 21 - Niccolň Machiavelli, Italian writer and statesman (born 1469)
- July 28 - Rodrigo de Bastidas, Spanish conquistador and explorer
- November 28 - Jerome Emser, German theologian (b. 1477)
- Boabdil, last Moorish king of Granada
- Charles III, Duke of Bourbon, Count of Montpensier and Dauphin of Auvergne (born 1490)
- Francesco Colonna, Italian Dominican priest (born 1433)
- Thomas Docwra, Grand Prior of the Knights Hospitaller (born 1458)
- Felix Manz, Swiss Anabaptist
- Cristoforo Solari, Italian sculptor and architect
- Jan 'Ciezki' Tarnowski, Polish nobleman
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