The NCI/VA Agreement on Clinical Trials: Questions and Answers

The Cancer Centers Program of the National Cancer Institute supports major academic and research institutions throughout the United States to sustain broad-based, coordinated, interdisciplinary programs in cancer research. These institutions are characterized by scientific excellence and the capability to integrate a diversity of research approaches to focus on the problem of cancer. The NCI and its Cancer Centers Program are dedicated to the advancement of cancer research to ultimately impact on the reduction of cancer incidence, morbidity, and mortality.

Several cancer centers existed in the late 1960s, but it was the National Cancer Act of 1971 that strengthened the program by authorizing the establishment of 15 new cancer centers while continuing to support existing ones. The passage of the Act also dramatically transformed the centers’ structure and broadened the scope of their mission to include all aspects of basic, clinical, and cancer control research. Today, 60 NCI-designated cancer centers continue to work toward creating new and innovative approaches to cancer research. Through interdisciplinary efforts, cancer centers can effectively move this research from the laboratory into clinical trials and finally into clinical practice.

NCI-designated cancer centers may be a freestanding operation, a center within an academic institution, or a formal consortium under centralized leadership. But all NCI-designated cancer centers must meet the same scientific, organizational, and administrative criteria.

Cancer centers seeking NCI-designation must first apply for an NCI Cancer Center Support grant. Application for NCI-designation is voluntary and is awarded through a peer-review process. Institutes that are awarded the grant are then recognized as NCI-designated. All NCI-designated cancer centers receive substantial financial support from NCI grants and are reevaluated each time their Cancer Center Support grant comes up for renewal.

The NCI recognizes two types of centers: Cancer Centers and Comprehensive Cancer Centers. Each type of center has special characteristics and capabilities for organizing new programs of research that can take advantage of important new findings and address timely research questions. It is important to note, however, that the terms NCI-designated Comprehensive Cancer Center and NCI-designated Cancer Center do not denote a difference in the quality of care they provide to patients.

Facilities designated Cancer Centers generally conduct a combination of basic, population sciences, and clinical research, and are encouraged to stimulate collaborative research involving more than one field of study. Several of these centers conduct only laboratory research and do not provide patient care. The NCI-designated Cancer Centers that do provide patient care are also expected to conduct early phase, innovative clinical trials and to participate in the NCI cooperative groups.

NCI-designated Comprehensive Cancer Centers conduct research and provide services directly to cancer patients. These facilities must demonstrate expertise in each of three areas: laboratory, clinical, and behavioral and population-based research. Comprehensive Cancer Centers are expected to initiate and conduct early phase, innovative clinical trials and to participate in the NCI’s cooperative groups by providing leadership and recruiting patients for trials. Comprehensive Cancer Centers must also conduct activities in outreach and education, and provide information on advances in healthcare for both healthcare professionals and the public.

Below is a list of the NCI-designated cancer centers. Additional information about the Cancer Centers Program can be found on the Cancer Centers Branch Web site at on the Internet.

Cancer Centers** and Comprehensive* Cancer Centers Supported by NCI

Information about referral procedures, treatment costs, and services available to patients can be obtained by contacting the individual cancer centers listed below.

ALABAMA University of Alabama at Birmingham Comprehensive Cancer Center*

1824 Sixth Avenue South
Birmingham, AL 35294–3300



Internet Web site:
ARIZONA Arizona Cancer Center*
Address: The University of Arizona
1515 North Campbell Avenue
Post Office Box 245024
Tucson, AZ  85724
Telephone: 520–626–2900
Internet Web site:
Mayo Clinic Cancer Center—Scottsdale*
Address: 13400 East Shea Boulevard
Scottsdale, AZ 85259
Telephone: 480–301–8484 or 480–301–1735
Internet Web site:

CALIFORNIA The Burnham Institute**°
  Address: 10901 North Torrey Pines Road
La Jolla, CA 92037
  Telephone: 8586463100
  Internet Web site:
  Chao Family Comprehensive Cancer Center*
Address: University of California, Irvine
Building 23, Route 81
101 The City Drive
Orange, CA 92868
Telephone: 714–456–8200
Internet Web site: 
City of Hope*
Address: Cancer Center and Beckman Research Institute
1500 East Duarte Road
Duarte, CA 91010–3000

626–256–4673 1–800–826–4673

Internet Web site: 
Jonsson Comprehensive Cancer Center at UCLA*
Address: 8–684 Factor Building
UCLA Box 951781
Los Angeles, CA 90095–1781
Telephone: 310–825–5268
Internet Web site: 
UC Davis Cancer Center**
Address: University of California, Davis
4501 X Street
Sacramento, CA 95817
Telephone: 1–800–362–5566
Internet Web site: 
Rebecca and John Moores University of California, San Diego Cancer Center*
Address: 9500 Gilman Drive
La Jolla, CA 92093–0658
Telephone: 858–534–7600
Internet Web site: 
The Salk Institute for Biological Studies** °
Address: Post Office Box 85800
10010 North Torrey Pines Road
La Jolla, CA 92037
Telephone: 8584534100
Internet Web site:
University of California, San Francisco Comprehensive Cancer Center*
Address: Box 0128, UCSF
1600 Divisadero Street
San Francisco, CA 94143–0128
Telephone: 1–800–888–8664
Internet Web site: 
USC/Norris Comprehensive Cancer Center and Hospital*
Address: 1441 Eastlake Avenue
Los Angeles, CA 90033–0804
Telephone: 323–865–3000
Internet Web site: 
COLORADO University of Colorado Cancer Center*
Address: Anschutz Cancer Pavilion
Box F–704
1665 North Ursula Street
Aurora, CO 80010
Telephone: 720–848–0300
Internet Web site: 
CONNECTICUT Yale Cancer Center*
Address: Yale University School of Medicine
333 Cedar Street
Post Office Box 208028
New Haven, CT 06520–8028
Telephone: 203–785–4095 
Internet Web site: 
DISTRICT OF COLUMBIA Lombardi Cancer Center*
Address: Georgetown University Medical Center
3800 Reservoir Road, NW.
Washington, DC 20057
Telephone: 202–444–4000
Internet Web site: 
FLORIDA H. Lee Moffitt Cancer Center & Research Institute at the University of South Florida*
Address: 12902 Magnolia Drive
Tampa, FL 33612–9497
Telephone: 813–972–4673
Internet Web site: 
Mayo Clinic Cancer Center—Jacksonville*
Address: 4500 San Pablo Road
Jacksonville, FL 32224
Telephone: 904–953–2272
Internet Web site:
HAWAII Cancer Research Center of Hawaii**
Address: 1236 Lauhala Street
Honolulu, HI 96813
Telephone: 808–586–3010 
Internet Web site:
ILLINOIS The Robert H. Lurie Comprehensive Cancer Center*
Address: Northwestern University
Olson Pavilion 8250
303 East Chicago Avenue  
Chicago, IL 60611
Telephone: 312–908–5250
Internet Web site:
University of Chicago Cancer Research Center**
Address: Mail Code 2115
5841 South Maryland Avenue
Chicago, IL 60637–1470
Telephone: 773–702–9200
Internet Web site:
INDIANA Indiana University Cancer Center**
Address: 535 Barnhill Drive
Indianapolis, IN 46202–5289
Telephone: 317–278–4822
Internet Web site: 
Purdue Cancer Center** °
Address: Hansen Life Sciences Research Building
Purdue University
201 South University Street
West Lafayette, IN 479072064
Telephone: 7654949129
Internet Web site:
IOWA The Holden Comprehensive Cancer Center at The University of Iowa*
Address: Room 5970–Z JPP
200 Hawkins Drive
Iowa City, IA 52242–1009
Telephone: 1–800–777–8442
Internet Web site:
MAINE The Jackson Laboratory** °
Address: 600 Main Street
Bar Harbor, ME 046090800
Telephone: 2072886000
Internet Web site:
MARYLAND Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins*
Address: The Harry and Jeanette Weinberg Building
Suite 1100
401 North Broadway
Baltimore, MD 21231–2410
Telephone: 410–955–8964
Internet Web site:
MASSACHUSETTS Dana-Farber Cancer Institute*
Address: 44 Binney Street
Boston, MA 02115
Telephone: 1–866–408–3324
Internet Web site: 
MIT Center for Cancer Research** °
Address: Room E17110
Massachusetts Institute of Technology
77 Massachusetts Avenue
Cambridge, MA 02139 4307
Telephone: 6172538511
Internet Web site:
MICHIGAN Barbara Ann Karmanos Cancer Institute*
Operating the Meyer L. Prentis Comprehensive Cancer Center of Metropolitan Detroit
Address: Wertz Clinical Cancer Center
4100 John R Street
Detroit, MI 48201–1379
Telephone: 1–800–527–6266
Internet Web site: 
  University of Michigan Comprehensive Cancer Center*
Address: 1500 East Medical Center Drive
Ann Arbor, MI 48109–0944
Telephone: 1–800–865–1125
Internet Web site: 
MINNESOTA Mayo Clinic Cancer Center*
Address: 200 First Street, SW.
Rochester, MN 55905
Telephone: 507–284–2111
Internet Web site: 
University of Minnesota Cancer Center*
Address: Mayo Mail Code 806
420 Delaware Street, SE.
Minneapolis, MN 55455
Telephone: 612–624–8484
Internet Web site: 
MISSOURI Siteman Cancer Center**
Address: Barnes-Jewish Hospital and 
Washington University School of Medicine
Box 8100
660 South Euclid Avenue
St. Louis, MO 63110–1093
Telephone: 314–747–7222
Internet Web site: 
NEBRASKA UNMC Eppley Cancer Center**
Address: University of Nebraska Medical Center
986805 Nebraska Medical Center
Omaha, NE 68198–6805
Telephone: 402–559–4238
Internet Web site: 
NEW HAMPSHIRE Norris Cotton Cancer Center*
Address: Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon, NH 03756–0002
Telephone: 603–653–9000
Internet Web site:
NEW JERSEY The Cancer Institute of New Jersey*
Address: 195 Little Albany Street
New Brunswick, NJ 08903–2681
Telephone: 732–235–2465
Internet Web site:
NEW YORK Albert Einstein Cancer Center**
Address: Albert Einstein College of Medicine
1300 Morris Park Avenue
Bronx, NY 10461
Telephone: 718–430–2302
Internet Web site: 
Cold Spring Harbor Laboratory**°
Address: Post Office Box 100
1 Bungtown Road
Cold Spring Harbor, NY 11724
Telephone: 5163678397
Internet Web site:
Herbert Irving Comprehensive Cancer Center*
Address: New York-Presbyterian Hospital
Columbia University Medical Center
PH 18, Room 200
622 West 168th Street
New York, NY 10032
Telephone: 1–877–697–9355
Internet Web site: 
Memorial Sloan-Kettering Cancer Center*
Address: 1275 York Avenue
New York, NY 10021
Telephone: 1–800–525–2225
Internet Web site: 
NYU Cancer Institute**
Address: New York University Cancer Institute
550 First Avenue
New York, NY 10016
Telephone: 212–263–6485
Internet Web site: 
Roswell Park Cancer Institute*
Address: Elm and Carlton Streets
Buffalo, NY 14263–0001
Telephone: 1–800–767–9355 
Internet Web site: 
NORTH CAROLINA Comprehensive Cancer Center of Wake Forest University*
Address: Wake Forest University Baptist Medical Center
Medical Center Boulevard
Winston-Salem, NC 27157–1082
Telephone: 336–716–4464
Internet Web site: 
Duke Comprehensive Cancer Center*
Address: Duke University Medical Center
Box 3843
301 MSRB
Durham, NC 27710
Telephone: 919–684–3377
Internet Web site: 
  UNC Lineberger Comprehensive Cancer Center*
Address: School of Medicine 
University of North Carolina at Chapel Hill
Campus Box 7295
Chapel Hill, NC 27599–7295
Telephone: 919–966–3036
Internet Web site: 
OHIO Ireland Cancer Center*
Address: University Hospitals HealthSystem
11100 Euclid Avenue
Cleveland, OH 44106–5065
Telephone: 216–844–5432
Internet Web site: 
  The Ohio State University Comprehensive Cancer Center*
Address: The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
Suite 519
300 West 10th Avenue
Columbus, OH 43210–1240
Telephone: 1–800–293–5066
Internet Web site: 
OREGON OHSU Cancer Institute**
Address: The Oregon Health Sciences University Cancer Institute
3181 Southwest Sam Jackson Park Road
Portland, OR 97239–3098
Telephone: 503–494–1617
Internet Web site:  
PENNSYLVANIA Abramson Cancer Center of the University of Pennsylvania*
Address: 15th Floor, Penn Tower
3400 Spruce Street
Philadelphia, PA 19104–4283
Telephone: 215–662–4000
Internet Web site:
  Fox Chase Cancer Center*
Address: 333 Cottman Avenue
Philadelphia, PA 19111–2497
Telephone: 215–728–2570
Internet Web site: 
Kimmel Cancer Center**
Address: Thomas Jefferson University
Bluemle Life Sciences Building
233 South 10th Street
Philadelphia, PA 19107–5541
Telephone: 1–888–955–1212
Internet Web site:
University of Pittsburgh Cancer Institute*
Address: 5150 Centre Avenue
Pittsburgh, PA 15232
Telephone: 412–647–2811
Internet Web site: 
Wistar Institute** °
Address: 3601 Spruce Street
Philadelphia, PA 19104
Telephone: 2158983700
Internet Web site:
TENNESSEE St. Jude Children’s Research Hospital**
Address: 332 North Lauderdale Street
Memphis, TN 38105–2794
Telephone: 901–495–3300
Internet Web site: 
The Vanderbilt-Ingram Cancer Center*
Address: Vanderbilt University
691 Preston Building
Nashville, TN 37232–6838
Telephone: 615–936–1782
615–936–5847 or 1–800–811–8480
Internet Web site: 
TEXAS San Antonio Cancer Institute**
Address: 7703 Floyd Curl Drive
San Antonio, TX 78229
Telephone: 210–567–2710
Internet Web site:
The University of Texas M. D. Anderson Cancer Center*
Address: 1515 Holcombe Boulevard
Houston, TX 77030
Telephone: 713–792–6161 
Internet Web site:
UTAH Huntsman Cancer Institute**
Address: University of Utah
2000 Circle of Hope
Salt Lake City, UT 84112
Telephone: 801–585–0303
Internet Web site: 
VERMONT Vermont Cancer Center*
Address: University of Vermont
Farrell Hall
210 Colchester Avenue
Burlington, VT 05405
Telephone: 802–656–4414
Internet Web site: 
VIRGINIA Massey Cancer Center**
Address: Virginia Commonwealth University
401 College Street
Post Office Box 980037
Richmond, VA 23298–0037
Telephone: 804–828–0450
Internet Web site: 
  The Cancer Center at The University of Virginia** 
Address: University of Virginia Health System
Box 800334
Charlottesville, VA 22908
Telephone: 434–924–9333
Internet Web site:
WASHINGTON Fred Hutchinson Cancer Research Center*
Address: LA–205
Post Office Box 19024
1100 Fairview Avenue North
Seattle, WA 98109–1024
Telephone: 206–288–1024 or 1–800–804–8824
Internet Web site: 
WISCONSIN University of Wisconsin Comprehensive Cancer Center*
Address: 600 Highland Avenue, K5/601
Madison, WI 53792–6164
Telephone: 608–263–8600 
Internet Web site: